|
gptkbp:instanceOf
|
gptkb:virus
polyomavirus
|
|
gptkbp:abbreviation
|
gptkb:JCV
|
|
gptkbp:associatedWith
|
gptkb:AIDS
immunosuppression
kidney transplant
|
|
gptkbp:category
|
human virus
|
|
gptkbp:causesDisease
|
gptkb:progressive_multifocal_leukoencephalopathy
JC virus encephalopathy
JC virus meningitis
JC virus nephropathy
granule cell neuronopathy
|
|
gptkbp:detects
|
blood
PCR
serology
urine
cerebrospinal fluid
brain tissue
|
|
gptkbp:discoveredBy
|
Kazuo Yoshioka
M. ZuRhein
|
|
gptkbp:discoveredIn
|
1971
|
|
gptkbp:family
|
gptkb:Polyomaviridae
|
|
gptkbp:firstIsolatedFrom
|
brain tissue
patient with Hodgkin's lymphoma
|
|
gptkbp:genomeSize
|
~5.1 kb
|
|
gptkbp:genomeType
|
double-stranded DNA
|
|
gptkbp:genus
|
Orthopolyomavirus
|
|
gptkbp:hostCellReceptor
|
serotonin receptor 5-HT2A
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
JC virus
|
|
gptkbp:infects
|
humans
|
|
gptkbp:namedAfter
|
gptkb:John_Cunningham
|
|
gptkbp:order
|
Sepolyvirales
|
|
gptkbp:prevalence
|
common worldwide
50-80% in adults
|
|
gptkbp:relatedTo
|
BK virus
SV40
|
|
gptkbp:replicatesIn
|
gptkb:nucleus
|
|
gptkbp:riskFactor
|
organ transplantation
immunosuppression
HIV infection
monoclonal antibody therapy
|
|
gptkbp:structure
|
icosahedral capsid
non-enveloped
|
|
gptkbp:taxonRank
|
Human polyomavirus 2
|
|
gptkbp:transmissionRoute
|
oral route
respiratory route
urinary route
|
|
gptkbp:treatment
|
no specific antiviral therapy
|
|
gptkbp:bfsParent
|
gptkb:progressive_multifocal_leukoencephalopathy
gptkb:Progressive_multifocal_leukoencephalopathy
gptkb:Polyomaviridae
|
|
gptkbp:bfsLayer
|
7
|