Statements (24)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:alternativeName |
SV40 T antigen
|
| gptkbp:binds |
gptkb:p53
gptkb:retinoblastoma_protein |
| gptkbp:discoveredIn |
gptkb:Simian_Virus_40
|
| gptkbp:domain |
DNA-binding domain
ATPase domain helicase domain |
| gptkbp:encodedBy |
T antigen gene
|
| gptkbp:foundIn |
polyomavirus
|
| gptkbp:function |
viral replication
cell transformation regulation of viral gene expression |
| https://www.w3.org/2000/01/rdf-schema#label |
Large T antigen
|
| gptkbp:inhibitedBy |
tumor suppressor proteins
|
| gptkbp:interactsWith |
gptkb:DNA_polymerase_alpha
host cell proteins |
| gptkbp:locale |
gptkb:nucleus
|
| gptkbp:molecularWeight |
~94 kDa
|
| gptkbp:role |
oncogenesis
|
| gptkbp:usedIn |
molecular biology research
|
| gptkbp:bfsParent |
gptkb:SV40_virus
gptkb:T_antigen_(SV40) |
| gptkbp:bfsLayer |
8
|