|
gptkbp:instanceOf
|
gptkb:protein
gptkb:gene
|
|
gptkbp:alternativeName
|
gptkb:CD329
gptkb:Sialic_acid-binding_Ig-like_lectin_9
|
|
gptkbp:binds
|
sialic acid
|
|
gptkbp:cytoplasmicTail
|
contains ITIM motif
|
|
gptkbp:encodedBy
|
SIGLEC9 gene
|
|
gptkbp:Entrez_Gene_ID
|
27180
|
|
gptkbp:expressedIn
|
macrophages
monocytes
neutrophils
some NK cells
|
|
gptkbp:extracellularDomain
|
contains Ig-like domains
|
|
gptkbp:foundIn
|
gptkb:Homo_sapiens
|
|
gptkbp:function
|
cell surface receptor
immune regulation
|
|
gptkbp:hasImmunoreceptorTyrosine-basedInhibitoryMotif
|
true
|
|
gptkbp:HGNC_ID
|
HGNC:10877
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Siglec-9
|
|
gptkbp:involvedIn
|
inhibition of immune cell activation
apoptosis of neutrophils
|
|
gptkbp:locatedOnChromosome
|
gptkb:chromosome_19q13.4
|
|
gptkbp:memberOf
|
gptkb:immunoglobulin_superfamily
gptkb:Siglec_family
|
|
gptkbp:OMIM
|
604039
|
|
gptkbp:orthologIn
|
mouse (Siglec-E)
|
|
gptkbp:PDB
|
2ZG2
|
|
gptkbp:relatedTo
|
autoimmune diseases
inflammatory diseases
cancer immunology
|
|
gptkbp:structure
|
type I transmembrane protein
|
|
gptkbp:UniProtID
|
gptkb:Q9Y336
|
|
gptkbp:bfsParent
|
gptkb:sialic_acid-binding_immunoglobulin-like_lectins_(Siglecs)
gptkb:CD329
gptkb:Siglec_family
|
|
gptkbp:bfsLayer
|
8
|