Statements (30)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
cell surface receptor |
| gptkbp:alsoKnownAs |
gptkb:CD33
|
| gptkbp:associatedWith |
Alzheimer's disease risk
|
| gptkbp:binds |
sialic acid-containing glycans
|
| gptkbp:contains |
immunoglobulin-like domains
ITIM motif |
| gptkbp:encodedBy |
gptkb:CD33_gene
|
| gptkbp:Entrez_Gene_ID |
945
|
| gptkbp:expressedIn |
dendritic cells
macrophages myeloid cells monocytes granulocytes |
| gptkbp:foundIn |
gptkb:Homo_sapiens
|
| gptkbp:function |
inhibition of immune cell activation
cell-cell interaction |
| gptkbp:HGNC_ID |
1659
|
| https://www.w3.org/2000/01/rdf-schema#label |
Siglec-3
|
| gptkbp:inhibitedBy |
immune cell activation
|
| gptkbp:locatedOnChromosome |
chromosome 19q13.3
|
| gptkbp:memberOf |
gptkb:Siglec_family
|
| gptkbp:OMIM |
159590
|
| gptkbp:regulates |
inflammatory response
|
| gptkbp:significance |
acute myeloid leukemia marker
|
| gptkbp:structure |
type I transmembrane protein
|
| gptkbp:target |
gptkb:gemtuzumab_ozogamicin
|
| gptkbp:UniProtID |
P20138
|
| gptkbp:bfsParent |
gptkb:CD33
|
| gptkbp:bfsLayer |
7
|