Serotonin-Norepinephrine Reuptake Inhibitors

GPTKB entity

Predicate	Object
gptkbp:instanceOf	gptkb:class_of_antidepressant_drugs
gptkbp:abbreviation	gptkb:SNRIs
gptkbp:category	gptkb:antidepressant gptkb:benzodiazepine psychotropic medication
gptkbp:contraindication	uncontrolled hypertension concurrent use with MAOIs
gptkbp:contrastsWith	gptkb:SSRIs
gptkbp:example	gptkb:venlafaxine gptkb:desvenlafaxine gptkb:levomilnacipran gptkb:milnacipran gptkb:duloxetine
gptkbp:introducedIn	1990s
gptkbp:mechanismOfAction	inhibit reuptake of serotonin and norepinephrine
gptkbp:notable_for	affect both serotonin and norepinephrine
gptkbp:regulates	prescription only
gptkbp:riskFactor	gptkb:discontinuation_syndrome gptkb:serotonin_syndrome
gptkbp:routeOfAdministration	oral
gptkbp:sideEffect	gptkb:sexual_dysfunction nausea dizziness insomnia dry mouth increased blood pressure
gptkbp:usedFor	gptkb:major_depressive_disorder chronic pain anxiety disorders
gptkbp:bfsParent	gptkb:SNRIs
gptkbp:bfsLayer	8
http://www.w3.org/2000/01/rdf-schema#label	Serotonin-Norepinephrine Reuptake Inhibitors