desvenlafaxine

GPTKB entity

Statements (52)
Predicate Object
gptkbp:instanceOf gptkb:drug
antidepressant
norepinephrine reuptake inhibitor
gptkbp:approvedBy gptkb:FDA
2008
gptkbp:ATCCode N06AX23
gptkbp:availableOn extended-release tablet
gptkbp:bioavailability 80%
gptkbp:brand gptkb:Khedezla
gptkb:Pristiq
gptkbp:CASNumber 93413-62-8
gptkbp:category antidepressant
psychiatric medication
SNRI
gptkbp:chemicalFormula C16H25NO2
gptkbp:compatibleWith children
gptkbp:contraindication concurrent use with MAO inhibitors
hypersensitivity to desvenlafaxine
gptkbp:developedBy gptkb:Wyeth
gptkbp:drugClass norepinephrine reuptake inhibitor
gptkbp:eliminationHalfLife 11 hours
gptkbp:excretion kidneys
https://www.w3.org/2000/01/rdf-schema#label desvenlafaxine
gptkbp:legalStatus prescription only
gptkbp:mechanismOfAction inhibits reuptake of serotonin and norepinephrine
gptkbp:metabolism gptkb:CYP3A4
gptkb:venlafaxine
gptkbp:molecularWeight 263.38 g/mol
gptkbp:notRecommendedFor bipolar disorder
anxiety disorders
gptkbp:patentExpired 2017
gptkbp:pregnancyCategory C (US)
gptkbp:prescribes adults
gptkbp:proteinBinding 30%
gptkbp:relatedTo gptkb:venlafaxine
gptkbp:riskFactor gptkb:serotonin_syndrome
hypertension
increased suicidal thoughts in young adults
gptkbp:routeOfAdministration oral
gptkbp:sideEffect nausea
constipation
dizziness
insomnia
dry mouth
hyperhidrosis
gptkbp:usedFor gptkb:major_depressive_disorder
gptkbp:bfsParent gptkb:venlafaxine
gptkb:Serotonin-norepinephrine_reuptake_inhibitors
gptkb:Venlafaxine
gptkb:serotonin-norepinephrine_reuptake_inhibitors
gptkb:SNRIs
gptkbp:bfsLayer 7