|
gptkbp:instanceOf
|
gptkb:drug
substance abuse
|
|
gptkbp:alternativeName
|
anxiolytic
barbiturate
|
|
gptkbp:antidote
|
gptkb:flumazenil
|
|
gptkbp:broadcastOn
|
gptkb:Schedule_IV_(US_Controlled_Substances_Act)
|
|
gptkbp:chemicalFormula
|
fusion of benzene and diazepine rings
|
|
gptkbp:contraindication
|
gptkb:myasthenia_gravis
acute narrow-angle glaucoma
severe respiratory insufficiency
sleep apnea syndrome
|
|
gptkbp:discoveredBy
|
gptkb:Leo_Sternbach
|
|
gptkbp:example
|
gptkb:lorazepam
gptkb:midazolam
gptkb:clonazepam
gptkb:diazepam
gptkb:chlordiazepoxide
gptkb:oxazepam
gptkb:temazepam
gptkb:flurazepam
gptkb:nitrazepam
gptkb:triazolam
alprazolam
|
|
gptkbp:excretion
|
gptkb:kidney
|
|
gptkbp:hasWithdrawalSymptoms
|
anxiety
seizures
insomnia
agitation
tremors
|
|
gptkbp:interactsWith
|
gptkb:beer
opioids
barbiturates
antipsychotics
antihistamines
antidepressants
|
|
gptkbp:legalStatus
|
prescription only
|
|
gptkbp:marketedAs
|
1960
|
|
gptkbp:mechanismOfAction
|
positive allosteric modulator of GABA-A receptor
|
|
gptkbp:metabolism
|
liver
|
|
gptkbp:overdoseSymptoms
|
coma
respiratory depression
|
|
gptkbp:pregnancyCategory
|
D (varies by country and drug)
|
|
gptkbp:prototypeDrug
|
gptkb:diazepam
gptkb:chlordiazepoxide
|
|
gptkbp:riskFactor
|
tolerance
dependence
abuse potential
withdrawal symptoms
|
|
gptkbp:sideEffect
|
confusion
dizziness
drowsiness
impaired coordination
|
|
gptkbp:usedFor
|
insomnia
anxiety disorders
seizure disorders
muscle spasms
alcohol withdrawal
|
|
gptkbp:bfsParent
|
gptkb:Valerian
gptkb:Versed
gptkb:Sceletium_tortuosum
gptkb:Lyrica
|
|
gptkbp:bfsLayer
|
5
|