Statements (31)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
guanine nucleotide exchange factor |
| gptkbp:abbreviation |
ADP-ribosylation factor family GTPases
|
| gptkbp:activatedBy |
guanine nucleotide exchange factors (GEFs)
|
| gptkbp:binds |
gptkb:GDP
gptkb:GTP |
| gptkbp:decommissioned |
GTPase-activating proteins (GAPs)
|
| gptkbp:discoveredIn |
1980s
|
| gptkbp:foundIn |
eukaryotes
|
| gptkbp:function |
regulation of actin cytoskeleton
regulation of vesicle trafficking |
| https://www.w3.org/2000/01/rdf-schema#label |
ARF family GTPases
|
| gptkbp:memberOf |
gptkb:Ras_superfamily
|
| gptkbp:proteinFamily |
gptkb:ARF6
gptkb:ARF1 ARFRP1 ARL1 SAR1 |
| gptkbp:regulates |
signal transduction
lipid metabolism endocytosis exocytosis membrane trafficking Golgi apparatus function |
| gptkbp:subfamily |
gptkb:ARF
gptkb:ARL SAR ARFRP1 |
| gptkbp:bfsParent |
gptkb:ArfGAP
gptkb:Sec7_domain |
| gptkbp:bfsLayer |
7
|