|
gptkbp:instanceOf
|
gptkb:gene
|
|
gptkbp:alias
|
gptkb:SA2
gptkb:stromal_antigen_2
SA-2
|
|
gptkbp:alternativeSplicing
|
yes
|
|
gptkbp:associatedWith
|
gptkb:myeloid_leukemia
gptkb:glioblastoma
gptkb:Ewing_sarcoma
bladder cancer
|
|
gptkbp:biologicalProcess
|
DNA repair
chromosome segregation
chromatin binding
mitotic cell cycle
|
|
gptkbp:discoveredIn
|
1999
|
|
gptkbp:encodes
|
gptkb:Cohesin_subunit_SA-2
|
|
gptkbp:Entrez_Gene_ID
|
gptkb:ENSG00000101972
10735
|
|
gptkbp:expressedIn
|
various human tissues
|
|
gptkbp:fullName
|
gptkb:Stromal_Antigen_2
|
|
gptkbp:function
|
component of the cohesin complex
involved in DNA repair
involved in gene expression regulation
regulates sister chromatid cohesion
|
|
gptkbp:geneType
|
protein-coding
|
|
gptkbp:hasParalog
|
gptkb:STAG1
STAG3
|
|
gptkbp:hasTranscriptVariant
|
multiple
|
|
gptkbp:HGNC_ID
|
gptkb:HGNC:11390
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
STAG2 gene
|
|
gptkbp:interactsWith
|
gptkb:NIPBL
gptkb:RAD21
gptkb:SMC1A
gptkb:SMC3
|
|
gptkbp:length
|
1231 amino acids
|
|
gptkbp:locatedOnChromosome
|
X
Xq25
|
|
gptkbp:mutationAssociatedWith
|
genomic instability
loss-of-function
tumorigenesis
aneuploidy
|
|
gptkbp:OMIM
|
300826
|
|
gptkbp:orthologInMouse
|
gptkb:Stag2
|
|
gptkbp:orthologInZebrafish
|
stag2a
|
|
gptkbp:proteinFamily
|
STAG family
|
|
gptkbp:referenceGenome
|
gptkb:GRCh38
|
|
gptkbp:subcellularLocation
|
gptkb:nucleus
|
|
gptkbp:UniProtID
|
gptkb:Q8N3U4
|
|
gptkbp:bfsParent
|
gptkb:Stromal_antigen_2_protein
gptkb:stromal_antigen_2
|
|
gptkbp:bfsLayer
|
7
|