|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:alternativeName
|
gptkb:Transmembrane_protein_106B
gptkb:TMEM106B
|
|
gptkbp:associatedWith
|
frontotemporal lobar degeneration
|
|
gptkbp:biologicalProcess
|
protein binding
lysosome organization
|
|
gptkbp:cellularComponent
|
lysosomal membrane
|
|
gptkbp:disulfideBond
|
Cys214-Cys253
|
|
gptkbp:Entrez_Gene_ID
|
gptkb:ENSG00000166333
91972
|
|
gptkbp:expressedIn
|
gptkb:cancer
gptkb:kidney
brain
heart
liver
|
|
gptkbp:function
|
lysosomal protein
|
|
gptkbp:gene
|
gptkb:TMEM106B
|
|
gptkbp:glycosylation_site
|
Asparagine 183
|
|
gptkbp:HGNC_ID
|
gptkb:HGNC:24681
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Q8N3U4
|
|
gptkbp:length
|
274
|
|
gptkbp:locatedOnChromosome
|
gptkb:chromosome_7
|
|
gptkbp:location
|
7p21.3
|
|
gptkbp:molecularWeight
|
31,000
|
|
gptkbp:mutationAssociatedWith
|
risk factor for FTLD
|
|
gptkbp:OMIM
|
613413
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologInMouse
|
gptkb:Q5XI73
Q8C0V7
|
|
gptkbp:pathway
|
lysosome pathway
neurodegeneration pathway
|
|
gptkbp:PDB
|
gptkb:7Q6A
gptkb:7Q6B
gptkb:7Q6C
7Q6D
|
|
gptkbp:phosphorylates
|
Serine 183
|
|
gptkbp:protein_existence
|
evidence at protein level
|
|
gptkbp:proteinFamily
|
gptkb:TMEM106_family
|
|
gptkbp:RefSeq
|
gptkb:NP_001243086.1
|
|
gptkbp:reviewedBy
|
yes
|
|
gptkbp:sequenceStatus
|
complete
|
|
gptkbp:signalPeptide
|
1-19
|
|
gptkbp:subcellularLocation
|
lysosome membrane
|
|
gptkbp:topology
|
single-pass type II membrane protein
|
|
gptkbp:transmembraneDomains
|
1
yes
|
|
gptkbp:UniGene
|
gptkb:Hs.513682
|
|
gptkbp:UniProtID
|
gptkb:Q8N3U4
|
|
gptkbp:bfsParent
|
gptkb:STAG2
|
|
gptkbp:bfsLayer
|
6
|