|
gptkbp:instanceOf
|
gptkb:protein
gptkb:gene
|
|
gptkbp:alternativeName
|
SRIF-3
SS3R
somatostatin receptor 3
|
|
gptkbp:associatedWith
|
gptkb:Alzheimer's_disease
neuroendocrine tumors
pituitary adenomas
|
|
gptkbp:binds
|
gptkb:somatostatin
|
|
gptkbp:discoveredBy
|
1992
|
|
gptkbp:encodedBy
|
SSTR3 gene
|
|
gptkbp:Entrez_Gene_ID
|
6753
ENSG00000128272
|
|
gptkbp:expressedIn
|
gptkb:cancer
gptkb:kidney
brain
gastrointestinal tract
pancreas
|
|
gptkbp:family
|
somatostatin receptor family
|
|
gptkbp:fullName
|
somatostatin receptor type 3
|
|
gptkbp:function
|
gptkb:G_protein-coupled_receptor
mediates somatostatin effects
|
|
gptkbp:geneType
|
protein-coding
|
|
gptkbp:HGNC_ID
|
11332
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
SSTR3
|
|
gptkbp:inhibitedBy
|
cell growth
hormone secretion
|
|
gptkbp:length
|
418
|
|
gptkbp:locatedOnChromosome
|
gptkb:22q13.1
chromosome 22
|
|
gptkbp:location
|
gptkb:cell_membrane
|
|
gptkbp:modulatedBy
|
cell proliferation
neurotransmission
adenylate cyclase activity
cAMP levels
|
|
gptkbp:molecularWeight
|
46 kDa
|
|
gptkbp:OMIM
|
182457
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologInMouse
|
Sstr3
|
|
gptkbp:RefSeq
|
NM_001053
|
|
gptkbp:targetOfDrug
|
gptkb:somatostatin_analogs
|
|
gptkbp:transmembraneDomains
|
true
|
|
gptkbp:type
|
gptkb:Gi/o_protein_pathway
|
|
gptkbp:UniProtID
|
P48357
|
|
gptkbp:bfsParent
|
gptkb:somatostatin
gptkb:Somatostatin
|
|
gptkbp:bfsLayer
|
7
|