|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:binds
|
gptkb:gene
|
|
gptkbp:discoveredBy
|
gptkb:Peter_Goodfellow
|
|
gptkbp:domain
|
gptkb:HMG_box
|
|
gptkbp:expressedIn
|
various tissues
|
|
gptkbp:firstDescribed
|
1990
|
|
gptkbp:foundIn
|
animals
humans
|
|
gptkbp:fullName
|
gptkb:SRY-related_HMG-box_proteins
|
|
gptkbp:function
|
transcription factor
transcriptional regulation
sequence-specific DNA binding
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
SOX proteins
|
|
gptkbp:involvedIn
|
embryonic development
cell fate determination
sex determination
|
|
gptkbp:member
|
gptkb:SOX5
gptkb:SOX6
gptkb:SOX13
gptkb:SOX9
gptkb:SOX2
gptkb:SOX1
gptkb:SOX10
gptkb:SOX11
gptkb:SOX12
gptkb:SOX14
gptkb:SOX15
gptkb:SOX17
gptkb:SOX18
gptkb:SOX21
gptkb:SOX3
gptkb:SOX30
gptkb:SOX4
gptkb:SOX7
gptkb:SOX8
|
|
gptkbp:mutationAssociatedWith
|
gptkb:cancer
developmental disorders
sex reversal
|
|
gptkbp:orthologIn
|
invertebrates
vertebrates
|
|
gptkbp:proteinFamily
|
gptkb:SOX_gene_family
|
|
gptkbp:regulates
|
gene expression
neurogenesis
stem cell maintenance
chondrogenesis
cardiogenesis
endoderm formation
gonad development
oligodendrocyte differentiation
|
|
gptkbp:relatedTo
|
gptkb:SRY_protein
|
|
gptkbp:bfsParent
|
gptkb:SOX
|
|
gptkbp:bfsLayer
|
5
|