SRY-related HMG-box proteins

GPTKB entity

Predicate	Object
gptkbp:instanceOf	gptkb:protein
gptkbp:alsoKnownAs	gptkb:SOX_proteins
gptkbp:binds	gptkb:gene
gptkbp:discoveredIn	1990s
gptkbp:domain	HMG-box domain
gptkbp:encodedBy	SOX genes
gptkbp:foundIn	animals
gptkbp:function	transcription factor
https://www.w3.org/2000/01/rdf-schema#label	SRY-related HMG-box proteins
gptkbp:importantFor	embryonic development neurogenesis stem cell maintenance gonad development
gptkbp:includes	gptkb:SOX5 gptkb:SOX6 gptkb:SOX13 gptkb:SOX9 gptkb:SOX2 gptkb:SOX1 gptkb:SOX10 gptkb:SOX11 gptkb:SOX12 gptkb:SOX14 gptkb:SOX15 gptkb:SOX17 gptkb:SOX18 gptkb:SOX21 gptkb:SOX3 gptkb:SOX30 gptkb:SOX4 gptkb:SOX7 gptkb:SOX8
gptkbp:involvedIn	cell fate determination sex determination developmental processes
gptkbp:mutationAssociatedWith	developmental disorders sex reversal syndromes
gptkbp:namedAfter	gptkb:SRY_gene
gptkbp:regulates	gene expression
gptkbp:relatedTo	gptkb:SRY_protein
gptkbp:subfamily	gptkb:SOXD gptkb:SOXA gptkb:SOXB gptkb:SOXC gptkb:SOXE gptkb:SOXF gptkb:SOXG SOXH
gptkbp:bfsParent	gptkb:SOX_proteins
gptkbp:bfsLayer	6