|
gptkbp:instanceOf
|
gptkb:protein
gptkb:gene
|
|
gptkbp:alternativeName
|
gptkb:CD329
gptkb:Sialic_acid-binding_Ig-like_lectin_9
gptkb:Siglec-9
sialic acid binding Ig-like lectin 9
|
|
gptkbp:associatedWith
|
gptkb:cancer
autoimmune diseases
inflammatory diseases
|
|
gptkbp:binds
|
sialic acid
|
|
gptkbp:discoveredBy
|
Ajit Varki group
|
|
gptkbp:domain
|
immunoglobulin-like domain
|
|
gptkbp:encodes
|
gptkb:Sialic_acid-binding_Ig-like_lectin_9
|
|
gptkbp:Entrez_Gene_ID
|
27180
ENSG00000105492
|
|
gptkbp:expressedIn
|
gptkb:NK_cells
macrophages
immune cells
monocytes
neutrophils
|
|
gptkbp:firstDescribed
|
2000
|
|
gptkbp:function
|
immune response modulation
cell-cell interaction
|
|
gptkbp:glycosylation
|
yes
|
|
gptkbp:hasGeneCardsID
|
gptkb:SIGLEC9
|
|
gptkbp:hasRefSeqID
|
NM_014386
|
|
gptkbp:HGNC_ID
|
HGNC:10877
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
SIGLEC9
|
|
gptkbp:involvedIn
|
inhibition of immune cell activation
regulation of inflammation
|
|
gptkbp:KEGGID
|
hsa:27180
|
|
gptkbp:length
|
463 amino acids
|
|
gptkbp:locatedOnChromosome
|
gptkb:chromosome_19
19q13.4
|
|
gptkbp:location
|
gptkb:cell_membrane
gptkb:plasma_membrane
|
|
gptkbp:memberOf
|
SIGLEC family
|
|
gptkbp:modulatedBy
|
apoptosis
phagocytosis
cytokine production
|
|
gptkbp:molecularWeight
|
~51 kDa
|
|
gptkbp:motif
|
ITIM motif
|
|
gptkbp:OMIM
|
604039
|
|
gptkbp:orthologInMouse
|
Siglec-E
|
|
gptkbp:PDB
|
2ZG2
|
|
gptkbp:product
|
type I transmembrane protein
|
|
gptkbp:Reactome
|
R-HSA-6798695
|
|
gptkbp:target
|
therapeutic antibodies
|
|
gptkbp:UniProtID
|
gptkb:Q9Y336
|
|
gptkbp:bfsParent
|
gptkb:CD329
|
|
gptkbp:bfsLayer
|
8
|