Statements (26)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:alternativeSplicing |
multiple isoforms
|
| gptkbp:associatedWith |
gptkb:type_2_diabetes
obesity |
| gptkbp:domain |
gptkb:PH_domain
SH2 domain |
| gptkbp:Entrez_Gene_ID |
25970
ENSG00000169047 |
| gptkbp:function |
adaptor protein in signal transduction
|
| gptkbp:gene |
gptkb:SH2B1
|
| https://www.w3.org/2000/01/rdf-schema#label |
SH2B adapter protein 1
|
| gptkbp:interactsWith |
gptkb:JAK2
gptkb:insulin_receptor leptin receptor |
| gptkbp:involves |
insulin signaling
leptin signaling |
| gptkbp:locatedOnChromosome |
gptkb:16p11.2
|
| gptkbp:molecularWeight |
~90 kDa
|
| gptkbp:OMIM |
608937
|
| gptkbp:organism |
gptkb:Homo_sapiens
|
| gptkbp:orthologInMouse |
gptkb:Sh2b1
|
| gptkbp:subcellularLocation |
gptkb:nucleus
gptkb:cytoplasm |
| gptkbp:UniProtID |
gptkb:Q9NRF2
|
| gptkbp:bfsParent |
gptkb:SH2B1
|
| gptkbp:bfsLayer |
7
|