Statements (29)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:alternativeSplicing |
yes
|
| gptkbp:associatedWith |
obesity
insulin resistance |
| gptkbp:biologicalProcess |
protein binding
receptor binding adaptor protein |
| gptkbp:domain |
gptkb:PH_domain
SH2 domain |
| gptkbp:encodedBy |
SH2B1 gene
|
| gptkbp:foundIn |
gptkb:Homo_sapiens
|
| gptkbp:interactsWith |
gptkb:JAK2
gptkb:insulin_receptor |
| gptkbp:involvedIn |
signal transduction
|
| gptkbp:locatedOnChromosome |
gptkb:16p11.2
|
| gptkbp:location |
gptkb:nucleus
gptkb:cytoplasm |
| gptkbp:mutationAssociatedWith |
severe early-onset obesity
neurobehavioral abnormalities |
| gptkbp:orthologIn |
gptkb:Mus_musculus
gptkb:Rattus_norvegicus |
| gptkbp:regulates |
insulin signaling
growth hormone signaling neurotrophin signaling leptin signaling |
| gptkbp:UniProtID |
gptkb:Q9NRF2
|
| gptkbp:bfsParent |
gptkb:SH2B1
|
| gptkbp:bfsLayer |
7
|
| http://www.w3.org/2000/01/rdf-schema#label |
SH2B-1
|