Statements (23)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:chemical_compound
|
| gptkbp:alsoKnownAs |
gptkb:L-748,337
gptkb:Z-VAD-FMK |
| gptkbp:CASNumber |
187389-52-2
|
| gptkbp:category |
caspase inhibitor
peptidyl fluoromethyl ketone |
| gptkbp:chemicalFormula |
C23H27FN6O4
|
| gptkbp:discoveredBy |
gptkb:Schering-Plough
|
| gptkbp:function |
pan-caspase inhibitor
|
| gptkbp:hasRole |
biological tool
|
| gptkbp:hasSMILES |
CC(C)C[C@@H](NC(=O)C(F)CC(=O)N[C@@H](Cc1ccccc1)C(=O)N)C(=O)O
|
| https://www.w3.org/2000/01/rdf-schema#label |
SCH 52365
|
| gptkbp:inhibitedBy |
gptkb:caspase-8
gptkb:caspase-1 gptkb:caspase-9 gptkb:caspase-3 gptkb:caspase-7 |
| gptkbp:mechanismOfAction |
irreversible inhibitor of caspases
|
| gptkbp:molecularWeight |
470.5 g/mol
|
| gptkbp:pubchemCID |
5311107
|
| gptkbp:usedIn |
apoptosis research
|
| gptkbp:bfsParent |
gptkb:C10483
|
| gptkbp:bfsLayer |
7
|