Statements (19)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:abbreviation |
Skp1-Cullin-F-box-Skp2 complex
|
| gptkbp:biologicalProcess |
cell cycle regulation
proteasomal degradation |
| gptkbp:component |
Rbx1
Skp1 Cullin-1 F-box protein Skp2 |
| gptkbp:discoveredBy |
late 1990s
|
| gptkbp:function |
E3 ubiquitin ligase
ubiquitination of target proteins |
| https://www.w3.org/2000/01/rdf-schema#label |
SCFSkp2 complex
|
| gptkbp:location |
gptkb:nucleus
|
| gptkbp:pathway |
gptkb:ubiquitin-proteasome_pathway
|
| gptkbp:regulates |
gptkb:G1/S_transition
|
| gptkbp:target |
gptkb:p21Cip1
gptkb:p27Kip1 |
| gptkbp:bfsParent |
gptkb:p21
|
| gptkbp:bfsLayer |
6
|