|
gptkbp:instanceOf
|
gptkb:chemical_compound
gptkb:coenzyme
|
|
gptkbp:abbreviation
|
gptkb:AdoMet
gptkb:SAM
|
|
gptkbp:biosynthesized_from
|
gptkb:ATP
methionine
|
|
gptkbp:CASNumber
|
29908-03-0
|
|
gptkbp:category
|
dietary supplement
methyl donor
nucleoside
sulfonium compound
|
|
gptkbp:chemicalFormula
|
C15H22N6O5S
|
|
gptkbp:chirality
|
L-form
|
|
gptkbp:contraindication
|
bipolar disorder
|
|
gptkbp:discoveredBy
|
gptkb:Giulio_Cantoni
|
|
gptkbp:discoveredIn
|
1952
|
|
gptkbp:foundIn
|
all living cells
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
S-adenosyl methionine
|
|
gptkbp:involves
|
methylation
transsulfuration pathway
aminopropylation
polyamine biosynthesis
transmethylation
transsulfuration
|
|
gptkbp:IUPACName
|
gptkb:S-adenosyl-L-methionine
|
|
gptkbp:KEGGID
|
C00019
|
|
gptkbp:meltingPoint
|
~190°C (decomposes)
|
|
gptkbp:MeSH_ID
|
D012490
|
|
gptkbp:molecularWeight
|
398.44 g/mol
|
|
gptkbp:predecessor
|
gptkb:methylthioadenosine
gptkb:S-adenosylhomocysteine
polyamines
homocysteine
|
|
gptkbp:produced_by_enzyme
|
gptkb:methionine_adenosyltransferase
|
|
gptkbp:PubChem_CID
|
gptkb:DB00118
gptkb:CHEMBL418
34755
CHEBI:16810
|
|
gptkbp:role
|
methyl group donor
precursor in biosynthesis
|
|
gptkbp:sideEffect
|
anxiety
sweating
insomnia
gastrointestinal upset
|
|
gptkbp:solubility
|
soluble
|
|
gptkbp:UNII
|
Q9Q0T007D9
|
|
gptkbp:used_as_supplement_for
|
gptkb:depression
gptkb:liver_disease
osteoarthritis
|
|
gptkbp:used_in
|
DNA methylation
RNA methylation
protein methylation
phospholipid methylation
|
|
gptkbp:bfsParent
|
gptkb:SAM
|
|
gptkbp:bfsLayer
|
6
|