|
gptkbp:instanceOf
|
gptkb:drug
biologic medication
|
|
gptkbp:activeIngredient
|
gptkb:interferon_alfa-2a
|
|
gptkbp:affiliatedWith
|
antineoplastic agents
interferons
immunostimulants
|
|
gptkbp:approvalYear
|
1986
|
|
gptkbp:approvedBy
|
gptkb:FDA
|
|
gptkbp:ATCCode
|
gptkb:L03AB02
|
|
gptkbp:CASNumber
|
76543-88-9
|
|
gptkbp:contraindication
|
autoimmune hepatitis
severe psychiatric disorders
|
|
gptkbp:discontinued
|
2013
true
|
|
gptkbp:form
|
solution for injection
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Roferon-A
|
|
gptkbp:legalStatus
|
prescription only
|
|
gptkbp:manufacturer
|
gptkb:Roche
|
|
gptkbp:marketedIn
|
gptkb:Europe
gptkb:Japan
gptkb:United_States
|
|
gptkbp:mechanismOfAction
|
immunomodulation
antiviral activity
antiproliferative activity
|
|
gptkbp:origin
|
recombinant DNA technology
|
|
gptkbp:pregnancyCategory
|
C (US)
|
|
gptkbp:product
|
cytokine
|
|
gptkbp:PubChem_CID
|
gptkb:DB00034
none
|
|
gptkbp:routeOfAdministration
|
intramuscular injection
subcutaneous injection
|
|
gptkbp:sideEffect
|
gptkb:depression
gptkb:anemia
fatigue
thrombocytopenia
leukopenia
flu-like symptoms
|
|
gptkbp:UNII
|
P18312A3XW
|
|
gptkbp:usedFor
|
gptkb:hairy_cell_leukemia
gptkb:Kaposi's_sarcoma
gptkb:chronic_hepatitis_C
leukemia
renal cell carcinoma
chronic hepatitis B
|
|
gptkbp:bfsParent
|
gptkb:DB00021
gptkb:F._Hoffmann-La_Roche_AG
|
|
gptkbp:bfsLayer
|
7
|