Statements (31)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:enzyme
|
| gptkbp:activity |
endoribonuclease
cleaves single phosphodiester bond |
| gptkbp:alternativeName |
gptkb:ribonuclease_P
|
| gptkbp:component |
gptkb:protein
gptkb:gene |
| gptkbp:discoveredBy |
gptkb:Thomas_Cech
gptkb:Sidney_Altman |
| gptkbp:EC_number |
3.1.26.5
|
| gptkbp:firstRibozymeDiscovered |
true
|
| gptkbp:foundIn |
gptkb:Bacteria
archaea eukaryotes |
| gptkbp:function |
catalyzes removal of 5' leader sequence from pre-tRNA
|
| gptkbp:gene |
RPPH1 (in humans)
rnpB (in bacteria) |
| https://www.w3.org/2000/01/rdf-schema#label |
RNase P
|
| gptkbp:location |
nucleus (in eukaryotes)
chloroplasts (in plants) mitochondria (in eukaryotes) |
| gptkbp:NobelPrizeYear |
gptkb:1989_Nobel_Prize_in_Chemistry
|
| gptkbp:orthologIn |
gptkb:RNase_MRP
|
| gptkbp:requires |
tRNA maturation
|
| gptkbp:structure |
RNA-protein complex
|
| gptkbp:substrate |
gptkb:pre-tRNA
other small RNAs |
| gptkbp:subunit |
gptkb:C5_protein_(in_E._coli)
gptkb:M1_RNA_(in_E._coli) |
| gptkbp:type |
gptkb:enzyme
|
| gptkbp:bfsParent |
gptkb:RNase
|
| gptkbp:bfsLayer |
6
|