|
gptkbp:instanceOf
|
RNA molecule
biological catalyst
|
|
gptkbp:canBe
|
engineered in vitro
natural ribozymes
synthetic ribozymes
|
|
gptkbp:catalyzes
|
RNA cleavage
RNA ligation
peptide bond formation
|
|
gptkbp:component
|
gptkb:gene
gptkb:RNase_P
gptkb:spliceosome
|
|
gptkbp:discoveredBy
|
gptkb:Thomas_R._Cech
gptkb:Sidney_Altman
|
|
gptkbp:discoveredIn
|
1982
|
|
gptkbp:distinctFrom
|
protein enzymes
|
|
gptkbp:foundIn
|
gptkb:RNase_P
gptkb:hairpin_ribozyme
gptkb:hammerhead_ribozyme
gptkb:viroids
ribosome
self-splicing introns
|
|
gptkbp:function
|
gene regulation
RNA processing
catalysis of biochemical reactions
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Ribozymes
|
|
gptkbp:NobelPrizeYear
|
gptkb:1989_Nobel_Prize_in_Chemistry
|
|
gptkbp:relatedTo
|
gptkb:RNA_world_hypothesis
origin of life
|
|
gptkbp:requires
|
magnesium ions
divalent metal ions
|
|
gptkbp:structure
|
single-stranded RNA
secondary structure
tertiary structure
|
|
gptkbp:type
|
gptkb:HDV_ribozyme
gptkb:VS_ribozyme
gptkb:glmS_ribozyme
gptkb:group_II_intron
gptkb:group_I_intron
gptkb:hairpin_ribozyme
gptkb:hammerhead_ribozyme
gptkb:hatchet_ribozyme
gptkb:perchlorate_ribozyme
gptkb:pistol_ribozyme
gptkb:twister-sister_ribozyme
gptkb:twister_ribozyme
|
|
gptkbp:usedIn
|
gptkb:biotechnology
gene therapy
molecular biology research
|
|
gptkbp:bfsParent
|
gptkb:Enzymes
|
|
gptkbp:bfsLayer
|
6
|