Statements (23)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:gene
|
| gptkbp:associatedWith |
genomic stability
immune system development |
| gptkbp:encodes |
Ring finger protein 8
|
| gptkbp:expressedIn |
various tissues
|
| gptkbp:foundIn |
gptkb:Mus_musculus
gptkb:Homo_sapiens |
| gptkbp:function |
E3 ubiquitin-protein ligase activity
|
| https://www.w3.org/2000/01/rdf-schema#label |
Rnf8
|
| gptkbp:interactsWith |
gptkb:UBC13
gptkb:MDC1 gptkb:RNF168 |
| gptkbp:involvedIn |
DNA damage response
ubiquitination |
| gptkbp:locatedOnChromosome |
6p21.3 (human)
|
| gptkbp:mutationAssociatedWith |
immunodeficiency
genomic instability |
| gptkbp:orthologIn |
RNF8 (human)
RNF8 (mouse) |
| gptkbp:regulates |
histone H2A ubiquitination
histone H2AX ubiquitination |
| gptkbp:bfsParent |
gptkb:RNF8
|
| gptkbp:bfsLayer |
8
|