E3 ubiquitin-protein ligase RNF8
GPTKB entity
Statements (28)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:alternativeName |
gptkb:RNF8
gptkb:RING_finger_protein_8 |
| gptkbp:associatedWith |
gptkb:cancer
|
| gptkbp:biologicalProcess |
protein ubiquitination
ubiquitin-protein transferase activity double-strand break repair |
| gptkbp:cellularComponent |
gptkb:nucleus
|
| gptkbp:domain |
RING finger domain
FHA domain |
| gptkbp:encodedBy |
RNF8 gene
|
| gptkbp:Entrez_Gene_ID |
9025
|
| gptkbp:function |
DNA damage response
E3 ubiquitin ligase activity |
| https://www.w3.org/2000/01/rdf-schema#label |
E3 ubiquitin-protein ligase RNF8
|
| gptkbp:interactsWith |
gptkb:UBC13
gptkb:53BP1 gptkb:MDC1 |
| gptkbp:length |
485 amino acids
|
| gptkbp:locale |
DNA damage foci
|
| gptkbp:locatedOnChromosome |
gptkb:6p21.3
|
| gptkbp:mass |
54 kDa
|
| gptkbp:organism |
gptkb:Homo_sapiens
|
| gptkbp:postTranslationalModification |
phosphorylation
|
| gptkbp:RefSeq |
NP_055155.2
|
| gptkbp:UniProtID |
Q9NYZ3
|
| gptkbp:bfsParent |
gptkb:RNF8
|
| gptkbp:bfsLayer |
8
|