Statements (29)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
peptide
biomarker |
| gptkbp:degradedBy |
kidneys
|
| gptkbp:discoveredBy |
gptkb:Donald_F._Steiner
Stefan S. Fajans |
| gptkbp:discoveredIn |
1967
|
| gptkbp:encodedBy |
gptkb:INS_gene
|
| gptkbp:function |
connects A and B chains of proinsulin
used to assess endogenous insulin secretion used to distinguish type 1 and type 2 diabetes |
| gptkbp:halfLife |
about 30 minutes
|
| https://www.w3.org/2000/01/rdf-schema#label |
C-peptide
|
| gptkbp:locatedOnChromosome |
gptkb:chromosome_11p15.5
|
| gptkbp:measures |
blood
urine |
| gptkbp:medicalUse |
diagnosis of insulinoma
differentiating factitious hypoglycemia monitoring beta cell function |
| gptkbp:molecularWeight |
about 3 kDa
|
| gptkbp:producedBy |
pancreatic beta cells
|
| gptkbp:range |
0.5–2.0 ng/mL (fasting, typical adult)
|
| gptkbp:relatedTo |
gptkb:insulin
proinsulin |
| gptkbp:releaseYear |
gptkb:insulin
|
| gptkbp:sequence |
31 amino acids
|
| gptkbp:structure |
linear polypeptide
|
| gptkbp:UniProtID |
P01308
|
| gptkbp:bfsParent |
gptkb:P04049
|
| gptkbp:bfsLayer |
7
|