Statements (33)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:amendedBy |
gptkb:histone_H2A
gptkb:histone_H3 |
| gptkbp:associatedWith |
chromatin remodeling
|
| gptkbp:component |
gptkb:Polycomb_Repressive_Complex_1
gptkb:Polycomb_Repressive_Complex_2 |
| gptkbp:contains |
gptkb:WD40_repeat
RING finger domain chromodomain |
| gptkbp:discoveredIn |
gptkb:Drosophila_melanogaster
|
| gptkbp:example |
gptkb:EED
gptkb:CBX2 gptkb:EZH2 gptkb:PHC1 gptkb:RING1B gptkb:SUZ12 BMI1 PCGF2 |
| gptkbp:firstDescribed |
1947
|
| gptkbp:foundIn |
eukaryotes
|
| gptkbp:function |
gene silencing
|
| https://www.w3.org/2000/01/rdf-schema#label |
Polycomb-group protein
|
| gptkbp:involvedIn |
epigenetic regulation
|
| gptkbp:mechanismOfAction |
histone modification
|
| gptkbp:namedAfter |
gptkb:Polycomb_gene
|
| gptkbp:opposedBy |
Trithorax-group protein
|
| gptkbp:proteinFamily |
gptkb:PcG
|
| gptkbp:regulates |
gptkb:Hox_genes
|
| gptkbp:role |
cancer progression
cell identity maintenance developmental gene regulation |
| gptkbp:bfsParent |
gptkb:Enhancer_of_zeste
|
| gptkbp:bfsLayer |
8
|