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gptkbp:instanceOf
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gptkb:protein
gptkb:enzyme
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gptkbp:catalyzes
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DNA-dependent RNA polymerase activity
|
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gptkbp:CTDContains
|
heptapeptide repeats
|
|
gptkbp:determines
|
X-ray crystallography
cryo-electron microscopy
|
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gptkbp:discoveredIn
|
1970s
|
|
gptkbp:encodedBy
|
multiple genes
|
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gptkbp:foundIn
|
eukaryotic cells
|
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gptkbp:fullName
|
gptkb:RNA_polymerase_II
|
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gptkbp:function
|
synthesizes messenger RNA (mRNA) in eukaryotes
|
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gptkbp:GO_term
|
GO:0003899 (DNA-directed 5'-3' RNA polymerase activity)
|
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gptkbp:hasCTD
|
C-terminal domain (CTD) on RBP1 subunit
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Pol II
|
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gptkbp:inhibitedBy
|
gptkb:alpha-amanitin
|
|
gptkbp:locale
|
cell nucleus
|
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gptkbp:regulates
|
phosphorylation of CTD
|
|
gptkbp:relatedTo
|
Pol I
Pol III
|
|
gptkbp:requires
|
transcription initiation
RNA processing
transcription elongation
general transcription factors
transcription termination
|
|
gptkbp:studiedIn
|
gptkb:Mus_musculus
gptkb:Saccharomyces_cerevisiae
gptkb:Homo_sapiens
|
|
gptkbp:subunit
|
gptkb:RBP1
gptkb:RBP10
gptkb:RBP11
gptkb:RBP12
gptkb:RBP13
gptkb:RBP14
gptkb:RBP15
gptkb:RBP16
gptkb:RBP17
gptkb:RBP18
gptkb:RBP19
gptkb:RBP2
gptkb:RBP20
gptkb:RBP3
gptkb:RBP4
gptkb:RBP5
gptkb:RBP6
gptkb:RBP7
gptkb:RBP8
gptkb:RBP9
|
|
gptkbp:transcribes
|
protein-coding genes
microRNAs (miRNAs)
some small nuclear RNAs (snRNAs)
|
|
gptkbp:UniProtID
|
P24928 (human RPB1 subunit)
|
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gptkbp:bfsParent
|
gptkb:RNA_polymerase_II
|
|
gptkbp:bfsLayer
|
7
|