|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:alternativeName
|
gptkb:RBP
Retinol-binding protein, plasma
|
|
gptkbp:associatedWith
|
retinal dystrophy
microphthalmia
Mendelian susceptibility to mycobacterial disease
|
|
gptkbp:binds
|
gptkb:retinol
gptkb:transthyretin
|
|
gptkbp:component
|
extracellular region
|
|
gptkbp:discoveredBy
|
Richard D. Goodman
|
|
gptkbp:discoveredIn
|
1968
|
|
gptkbp:encodedBy
|
RBP4 gene
|
|
gptkbp:Entrez_Gene_ID
|
5950
ENSG00000138207
|
|
gptkbp:expressedIn
|
liver
adipose tissue
|
|
gptkbp:fullName
|
Retinol-binding protein 4
|
|
gptkbp:function
|
retinol binding
transports retinol (vitamin A) in blood
|
|
gptkbp:gene
|
gptkb:RBP4
|
|
gptkbp:GOProcess
|
retinoid metabolic process
|
|
gptkbp:HGNC_ID
|
9917
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
RBP4
|
|
gptkbp:isSecreted
|
true
|
|
gptkbp:length
|
201 amino acids
|
|
gptkbp:locatedOnChromosome
|
gptkb:chromosome_10
|
|
gptkbp:location
|
10q23-q24
|
|
gptkbp:molecularWeight
|
21 kDa
|
|
gptkbp:mutationAssociatedWith
|
can cause night blindness
can cause retinol deficiency
|
|
gptkbp:numberOfExons
|
6
|
|
gptkbp:OMIM
|
180250
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologIn
|
gptkb:Bos_taurus
gptkb:Mus_musculus
gptkb:Rattus_norvegicus
|
|
gptkbp:PDB
|
2WQ6
|
|
gptkbp:postTranslationalModification
|
phosphorylation
glycosylation
|
|
gptkbp:proteinFamily
|
lipocalin
|
|
gptkbp:RefSeq
|
NM_006744
|
|
gptkbp:signalPeptide
|
true
|
|
gptkbp:significance
|
linked to insulin resistance
linked to obesity
linked to type 2 diabetes
|
|
gptkbp:structure
|
single polypeptide chain
|
|
gptkbp:subcellularLocation
|
blood plasma
extracellular space
|
|
gptkbp:UniProtID
|
P02753
|
|
gptkbp:bfsParent
|
gptkb:RNA_polymerase_II
|
|
gptkbp:bfsLayer
|
7
|