Statements (49)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:alsoKnownAs |
POU proteins
|
| gptkbp:binds |
gptkb:gene
|
| gptkbp:discoveredIn |
1980s
|
| gptkbp:domain |
homeodomain
POU domain |
| gptkbp:example |
gptkb:Oct4
gptkb:POU5F1 gptkb:POU1F1 gptkb:POU2F1 gptkb:POU4F1 gptkb:POU6F1 Brn3a Oct1 POU3F2 POU3F3 Pit1 Unc-86 |
| gptkbp:foundIn |
animals
|
| gptkbp:function |
transcription factor
|
| https://www.w3.org/2000/01/rdf-schema#label |
Pit-Oct-Unc proteins
|
| gptkbp:motif |
gptkb:POU-specific_domain
gptkb:POU_homeodomain linker region |
| gptkbp:namedAfter |
Oct-1
Pit-1 Unc-86 |
| gptkbp:regulates |
gene expression
pluripotency genes neuronal gene expression pituitary development immune response genes |
| gptkbp:role |
cell differentiation
development neurogenesis stem cell maintenance immune system regulation |
| gptkbp:studiedIn |
gptkb:C._elegans
gptkb:Drosophila_melanogaster mammals |
| gptkbp:subfamily |
POU1
POU2 POU3 POU4 POU5 POU6 POU7 |
| gptkbp:bfsParent |
gptkb:POU_family
|
| gptkbp:bfsLayer |
7
|