gptkbp:instanceOf
|
PharmGKB Drug Identifier
|
gptkbp:ATCCode
|
gptkb:B01AA03
|
gptkbp:CASNumber
|
gptkb:81-81-2
|
gptkbp:contraindication
|
pregnancy
uncontrolled hypertension
recent surgery
hemorrhagic tendencies
|
gptkbp:drugClass
|
gptkb:anticoagulant
|
gptkbp:hasBoxedWarning
|
major or fatal bleeding
|
gptkbp:hasExternalId
|
ChEBI:10037
ChemSpider:10442413
DrugBank:DB00682
KEGG:D08602
PubChem:54678486
RxNorm:11289
UNII:5Q7ZVV76EI
Wikipedia:Warfarin
|
gptkbp:hasFDALabel
|
https://www.pharmgkb.org/label/PA166104839
|
gptkbp:hasInChIKey
|
UJYFUPVWRZPMJE-UHFFFAOYSA-N
|
gptkbp:hasMolecularFormula
|
C19H16O4
|
gptkbp:hasPharmacogenomicAnnotation
|
gptkb:CYP2C9
CYP4F2
VKORC1
CALU
GGCX
|
gptkbp:hasPharmacogenomicGuideline
|
gptkb:CPIC
DPWG
|
gptkbp:hasPharmGKBAccessionId
|
PA128
|
gptkbp:hasPharmGKBUrl
|
https://www.pharmgkb.org/chemical/PA128
|
gptkbp:hasSMILES
|
CC(=O)CC(c1ccccc1)c2ccccc2O
|
https://www.w3.org/2000/01/rdf-schema#label
|
PharmGKB:PA128
|
gptkbp:indication
|
prevention of thrombosis
treatment of thromboembolic disorders
|
gptkbp:mechanismOfAction
|
vitamin K epoxide reductase inhibitor
|
gptkbp:molecularWeight
|
308.33
|
gptkbp:name
|
gptkb:warfarin
|
gptkbp:refersTo
|
gptkb:warfarin
|
gptkbp:routeOfAdministration
|
oral
|
gptkbp:sideEffect
|
bleeding
hemorrhage
skin necrosis
|
gptkbp:synonym
|
gptkb:Coumadin
gptkb:Jantoven
gptkb:Marevan
Warfarin sodium
|
gptkbp:target
|
gptkb:CYP2C9
CYP4F2
VKORC1
CALU
GGCX
|
gptkbp:bfsParent
|
gptkb:HGNC:3113
gptkb:HGNC:2384
|
gptkbp:bfsLayer
|
8
|