|
gptkbp:instanceOf
|
opioid
|
|
gptkbp:alsoKnownAs
|
gptkb:Demerol
gptkb:meperidine
|
|
gptkbp:antidote
|
gptkb:naloxone
|
|
gptkbp:ATCCode
|
N02AB02
|
|
gptkbp:CASNumber
|
57-42-1
|
|
gptkbp:category
|
gptkb:phenylpiperidine
analgesic
opioid
|
|
gptkbp:cause
|
addiction
tolerance
dependence
|
|
gptkbp:chemicalFormula
|
C15H21NO2
|
|
gptkbp:contraindication
|
MAOI use
severe respiratory depression
|
|
gptkbp:controlledSubstanceSchedule
|
gptkb:Schedule_II_(US)
|
|
gptkbp:discoveredBy
|
gptkb:Otto_Eisleb
|
|
gptkbp:discoveredIn
|
1939
|
|
gptkbp:eliminationHalfLife
|
2.5–4 hours
|
|
gptkbp:hasMetabolite
|
normeperidine
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Pethidine
|
|
gptkbp:legalStatus
|
prescription only
|
|
gptkbp:marketedAs
|
1940s
|
|
gptkbp:MeSH_ID
|
D008575
|
|
gptkbp:metabolism
|
liver
|
|
gptkbp:molecularWeight
|
247.33 g/mol
|
|
gptkbp:origin
|
gptkb:Germany
|
|
gptkbp:pregnancyCategory
|
C (US)
|
|
gptkbp:PubChem_CID
|
4058
DB00454
|
|
gptkbp:riskFactor
|
seizures (with accumulation of normeperidine)
|
|
gptkbp:routeOfAdministration
|
oral
intramuscular
subcutaneous
intravenous
|
|
gptkbp:sideEffect
|
nausea
vomiting
constipation
dizziness
sweating
drowsiness
respiratory depression
|
|
gptkbp:target
|
gptkb:delta-opioid_receptor
gptkb:kappa-opioid_receptor
gptkb:mu-opioid_receptor
|
|
gptkbp:UNII
|
55D94103HL
|
|
gptkbp:usedFor
|
pain management
|
|
gptkbp:usedIn
|
obstetrics
acute pain
preoperative medication
|
|
gptkbp:bfsParent
|
gptkb:List_I_(Canada)
|
|
gptkbp:bfsLayer
|
7
|