Peroxisome proliferator-activated receptor gamma protein
GPTKB entity
Statements (33)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:alias |
gptkb:NR1C3
gptkb:PPAR-gamma |
| gptkbp:associatedWith |
gptkb:type_2_diabetes
gptkb:metabolic_syndrome obesity atherosclerosis |
| gptkbp:domain |
DNA-binding domain
ligand-binding domain |
| gptkbp:encodedBy |
PPARG gene
|
| gptkbp:formsComplexWith |
retinoid X receptor
|
| gptkbp:foundIn |
gptkb:Homo_sapiens
|
| gptkbp:function |
transcription factor
nuclear receptor |
| https://www.w3.org/2000/01/rdf-schema#label |
Peroxisome proliferator-activated receptor gamma protein
|
| gptkbp:involvedIn |
insulin sensitivity
inflammation regulation macrophage differentiation |
| gptkbp:locatedIn |
cell nucleus
|
| gptkbp:locatedOnChromosome |
3p25
|
| gptkbp:memberOf |
gptkb:nuclear_hormone_receptor_family
|
| gptkbp:modulatedBy |
prostaglandins
fatty acids eicosanoids |
| gptkbp:OMIM |
601487
|
| gptkbp:PDB |
3CS8
|
| gptkbp:regulates |
lipid metabolism
glucose metabolism adipogenesis |
| gptkbp:target |
thiazolidinedione drugs
|
| gptkbp:UniProtID |
P37231
|
| gptkbp:bfsParent |
gptkb:PPARG
|
| gptkbp:bfsLayer |
8
|