|
gptkbp:instanceOf
|
transcription factor
nuclear receptor
|
|
gptkbp:activatedBy
|
gptkb:thiazolidinediones
prostaglandins
fatty acids
|
|
gptkbp:alias
|
gptkb:Peroxisome_proliferator-activated_receptor_gamma
gptkb:NR1C3
|
|
gptkbp:alternativeSplicing
|
PPAR-gamma1
PPAR-gamma2
|
|
gptkbp:associatedWith
|
gptkb:type_2_diabetes
gptkb:metabolic_syndrome
obesity
atherosclerosis
colon cancer
|
|
gptkbp:binds
|
PPRE (peroxisome proliferator response element)
|
|
gptkbp:discoveredBy
|
Bruce M. Spiegelman
|
|
gptkbp:encodedBy
|
PPARG gene
|
|
gptkbp:expressedIn
|
gptkb:skeletal_muscle
liver
adipose tissue
colon
macrophages
|
|
gptkbp:formsComplexWith
|
retinoid X receptor
|
|
gptkbp:HGNC_ID
|
9236
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
PPAR-gamma
|
|
gptkbp:involvedIn
|
insulin sensitivity
inflammation regulation
macrophage differentiation
|
|
gptkbp:locatedIn
|
cell nucleus
|
|
gptkbp:locatedOnChromosome
|
3p25
|
|
gptkbp:modulatedBy
|
gptkb:pioglitazone
gptkb:rosiglitazone
troglitazone
15d-PGJ2
ciglitazone
|
|
gptkbp:orthologIn
|
gptkb:mouse
gptkb:zebrafish
right
|
|
gptkbp:PDB
|
1PRG
2PRG
3DZY
|
|
gptkbp:regulates
|
gptkb:GLUT4
gptkb:LPL
gptkb:CD36
gptkb:adiponectin
lipid metabolism
glucose metabolism
adipogenesis
FABP4
|
|
gptkbp:target
|
antidiabetic drugs
|
|
gptkbp:UniProtID
|
P37231
|
|
gptkbp:bfsParent
|
gptkb:Peroxisome_proliferator-activated_receptor
|
|
gptkbp:bfsLayer
|
7
|