|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:alternativeName
|
IPF1
insulin promoter factor 1
|
|
gptkbp:associatedWith
|
gptkb:diabetes_mellitus
MODY4
|
|
gptkbp:discoveredBy
|
gptkb:Christopher_Wright
|
|
gptkbp:discoveredIn
|
1993
|
|
gptkbp:domain
|
homeodomain
|
|
gptkbp:encodedBy
|
PDX1 gene
|
|
gptkbp:Entrez_Gene_ID
|
ENSG00000139515
|
|
gptkbp:expressedIn
|
gptkb:duodenum
pancreas
|
|
gptkbp:fullName
|
Pancreatic and duodenal homeobox 1
|
|
gptkbp:function
|
transcription factor
regulates insulin gene expression
regulates pancreatic development
|
|
gptkbp:gene
|
gptkb:PDX1
|
|
gptkbp:HGNC_ID
|
HGNC:3750
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Pdx1
|
|
gptkbp:interactsWith
|
HNF1A
NeuroD1
MafA
|
|
gptkbp:locatedOnChromosome
|
chromosome 13q12.1
|
|
gptkbp:location
|
gptkb:nucleus
|
|
gptkbp:molecularWeight
|
31 kDa
|
|
gptkbp:mutationAssociatedWith
|
pancreatic agenesis
MODY4
|
|
gptkbp:OMIM
|
600733
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:phosphorylates
|
gptkb:Serine_61
Serine 268
|
|
gptkbp:RefSeq
|
NM_000209
|
|
gptkbp:regulates
|
gptkb:insulin
gptkb:somatostatin
gptkb:glucokinase
glucose transporter 2
|
|
gptkbp:speciesHomolog
|
mouse Pdx1
rat Pdx1
|
|
gptkbp:UniProtID
|
P52945
|
|
gptkbp:bfsParent
|
gptkb:pyridoxal_5'-phosphate_synthase
gptkb:PDX1
|
|
gptkbp:bfsLayer
|
8
|