|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:alternativeSplicing
|
yes
|
|
gptkbp:associatedWith
|
gptkb:pre-B-cell_acute_lymphoblastic_leukemia
|
|
gptkbp:binds_DNA
|
yes
|
|
gptkbp:discoveredBy
|
1990
|
|
gptkbp:domain
|
homeobox domain
Nuclear localization signal
PBC-A domain
PBC-B domain
|
|
gptkbp:encodedBy
|
gptkb:PBX1_gene
|
|
gptkbp:Entrez_Gene_ID
|
5087
ENSG00000115155
|
|
gptkbp:family
|
TALE homeobox
|
|
gptkbp:formsComplexWith
|
gptkb:MEIS_proteins
gptkb:HOX_proteins
|
|
gptkbp:function
|
gptkb:transcription_factor
|
|
gptkbp:gene
|
gptkb:PBX1
|
|
gptkbp:geneType
|
protein-coding
|
|
gptkbp:interactsWith
|
gptkb:PBX2
gptkb:PBX3
gptkb:HOXB1
gptkb:HOXC8
gptkb:HOXD10
gptkb:HOXD11
gptkb:HOXD13
gptkb:HOXD4
gptkb:HOXD9
gptkb:HOXA9
gptkb:MEIS1
gptkb:PREP1
MEIS2
MEIS3
|
|
gptkbp:involves
|
hematopoiesis
leukemogenesis
developmental regulation
|
|
gptkbp:locatedOnChromosome
|
1q23
|
|
gptkbp:location
|
gptkb:nucleus
|
|
gptkbp:molecularWeight
|
~47 kDa
|
|
gptkbp:OMIM
|
176310
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologInMouse
|
gptkb:Pbx1
|
|
gptkbp:orthologInZebrafish
|
pbx1a
pbx1b
|
|
gptkbp:postTranslationalModification
|
phosphorylation
sumoylation
acetylation
|
|
gptkbp:transcriptional_activity
|
activator
repressor
|
|
gptkbp:UniProtID
|
P40424
|
|
gptkbp:bfsParent
|
gptkb:Pbx1
|
|
gptkbp:bfsLayer
|
7
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Pbx-1
|