|
gptkbp:instanceOf
|
gptkb:drug
antineoplastic agent
|
|
gptkbp:approvalYear
|
1989
|
|
gptkbp:approvedBy
|
gptkb:FDA
|
|
gptkbp:ATCCode
|
L01XA02
|
|
gptkbp:brand
|
gptkb:Paraplatin
Carboplat
|
|
gptkbp:CASNumber
|
41575-94-4
|
|
gptkbp:discoveredBy
|
gptkb:Johnson_Matthey
|
|
gptkbp:eliminationHalfLife
|
1.5–3.6 hours
|
|
gptkbp:excretion
|
gptkb:kidney
|
|
gptkbp:genericName
|
gptkb:carboplatin
|
|
gptkbp:hasMolecularFormula
|
C6H12N2O4Pt
|
|
gptkbp:hasSMILES
|
O=C1O[Pt](N2CCCCC2)(O1)N3CCCCC3
|
|
gptkbp:hasUNII
|
Q20Q21Q62J
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Paraplatin
|
|
gptkbp:isAnalogOf
|
gptkb:cisplatin
|
|
gptkbp:KEGGID
|
D00217
|
|
gptkbp:legalStatus
|
prescription only
|
|
gptkbp:mechanismOfAction
|
DNA crosslinking
|
|
gptkbp:metabolism
|
non-enzymatic hydrolysis
|
|
gptkbp:pregnancyCategory
|
D (US)
|
|
gptkbp:PubChem_CID
|
gptkb:CHEMBL1379
DB00958
4470732
5311292
|
|
gptkbp:routeOfAdministration
|
intravenous
|
|
gptkbp:sideEffect
|
gptkb:anemia
nausea
vomiting
neutropenia
thrombocytopenia
myelosuppression
|
|
gptkbp:synonym
|
cis-diammine(1,1-cyclobutanedicarboxylato)platinum(II)
JM-8
NSC 241240
|
|
gptkbp:usedFor
|
gptkb:cancer
testicular cancer
head and neck cancer
|
|
gptkbp:bfsParent
|
gptkb:carboplatin
gptkb:Carboplatin
|
|
gptkbp:bfsLayer
|
7
|