Statements (60)
| Predicate | Object |
|---|---|
| gptkbp:instance_of |
gptkb:drug
|
| gptkbp:bfsLayer |
6
|
| gptkbp:bfsParent |
gptkb:Carboplatin_Mylan
|
| gptkbp:activities |
gptkb:weapon
|
| gptkbp:appointed_by |
oncology
intravenous injection |
| gptkbp:approves |
gptkb:FDA
|
| gptkbp:brand |
gptkb:Paraplatin
|
| gptkbp:can_be_used_with |
gptkb:paclitaxel
gptkb:etoposide |
| gptkbp:class |
platinum-based drug
|
| gptkbp:clinical_trial |
Phase II
pediatric oncology adult oncology |
| gptkbp:composed_of |
gptkb:chemical_compound
|
| gptkbp:contraindication |
severe renal impairment
|
| gptkbp:developed_by |
gptkb:cisplatin
|
| gptkbp:discovered_by |
1970s
|
| gptkbp:dosage_form |
injectable solution
|
| gptkbp:education |
regular blood tests
reporting side effects hydration before treatment avoidance of infections |
| gptkbp:excretion |
kidneys
|
| gptkbp:formulation |
solution for injection
|
| https://www.w3.org/2000/01/rdf-schema#label |
Carboplatin
|
| gptkbp:ingredients |
C6 H10 N2 O4 Pt
|
| gptkbp:interacts_with |
anticoagulants
live vaccines other nephrotoxic drugs NSAI Ds other chemotherapy drugs |
| gptkbp:invention |
US patent 4,088,726
|
| gptkbp:is_monitored_by |
blood counts
|
| gptkbp:is_used_for |
treating cancer
|
| gptkbp:metabolism |
liver
|
| gptkbp:packaging |
vials
|
| gptkbp:provides_information_on |
every 3 weeks
|
| gptkbp:research_areas |
personalized medicine
pharmacogenomics combination therapies drug resistance novel formulations |
| gptkbp:research_focus |
cancer therapy
|
| gptkbp:shelf_life |
24 months
|
| gptkbp:side_effect |
gptkb:fandom
fatigue nausea allergic reactions vomiting hearing loss thrombocytopenia bone marrow suppression neutropenia |
| gptkbp:storage |
room temperature
|
| gptkbp:targets |
gptkb:DJ
|
| gptkbp:used_in |
bladder cancer treatment
lung cancer treatment testicular cancer treatment ovarian cancer treatment |