Statements (23)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:alsoKnownAs |
peptidyl-prolyl cis-trans isomerase
|
| gptkbp:binds |
cyclosporin A
|
| gptkbp:biologicalProcess |
isomerase activity
|
| gptkbp:discoveredBy |
Fischer et al.
|
| gptkbp:domain |
cyclophilin-like domain
|
| gptkbp:EC_number |
5.2.1.8
|
| gptkbp:example |
gptkb:Cyclophilin_A
Cyclophilin B Cyclophilin D |
| gptkbp:firstDescribed |
1984
|
| gptkbp:foundIn |
prokaryotes
eukaryotes |
| gptkbp:function |
catalyzes cis-trans isomerization of proline imidic peptide bonds in oligopeptides
|
| https://www.w3.org/2000/01/rdf-schema#label |
cyclophilin
|
| gptkbp:inhibitedBy |
cyclosporin A
|
| gptkbp:proteinFamily |
PPIase
|
| gptkbp:role |
gptkb:mitochondrial_permeability_transition_pore
immunosuppression protein folding HIV-1 infection |
| gptkbp:bfsParent |
gptkb:PPIA
|
| gptkbp:bfsLayer |
8
|