Statements (25)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:drug
|
| gptkbp:alternativeName |
gptkb:glitazones
|
| gptkbp:approvedBy |
gptkb:FDA
|
| gptkbp:chemicalFormula |
thiazolidinedione ring
|
| gptkbp:compatibleWith |
type 1 diabetes
|
| gptkbp:contraindication |
heart failure
|
| gptkbp:discoveredIn |
1990s
|
| gptkbp:example |
gptkb:pioglitazone
gptkb:rosiglitazone |
| https://www.w3.org/2000/01/rdf-schema#label |
thiazolidinediones
|
| gptkbp:lowers |
blood glucose
|
| gptkbp:mechanismOfAction |
PPAR-gamma agonist
|
| gptkbp:metabolism |
liver
|
| gptkbp:pregnancyCategory |
C
|
| gptkbp:regulates |
insulin sensitivity
|
| gptkbp:routeOfAdministration |
oral
|
| gptkbp:sideEffect |
edema
weight gain bone fracture risk heart failure risk |
| gptkbp:usedFor |
gptkb:type_2_diabetes
|
| gptkbp:bfsParent |
gptkb:AMPK_pathway
gptkb:AMPK gptkb:vildagliptin |
| gptkbp:bfsLayer |
6
|