PLCD1

URI: https://gptkb.org/entity/PLCD1
GPTKB entity
Statements (31)
Predicate Object
gptkbp:instanceOf gptkb:gene
gptkbp:alias PLC-delta-1
PLC-δ1
gptkbp:alternativeSplicing yes
gptkbp:associatedWith hereditary leukonychia
gptkbp:biologicalProcess phospholipase C activity
gptkbp:cellularComponent gptkb:cytoplasm
gptkb:plasma_membrane
gptkbp:discoveredBy Kohda et al.
gptkbp:encodes phospholipase C delta-1 protein
gptkbp:Entrez_Gene_ID gptkb:ENSG00000138061
5333
gptkbp:expressedIn various tissues
gptkbp:firstDescribed 1993
gptkbp:fullName phospholipase C delta 1
gptkbp:function hydrolyzes phosphatidylinositol 4,5-bisphosphate
generates second messengers diacylglycerol and inositol 1,4,5-trisphosphate
gptkbp:geneType protein-coding
gptkbp:HGNC_ID 9066
https://www.w3.org/2000/01/rdf-schema#label PLCD1
gptkbp:involvedIn signal transduction
gptkbp:length 15 exons
gptkbp:locatedOnChromosome 3p22.2
gptkbp:mutationAssociatedWith leukonychia totalis
gptkbp:OMIM 602142
gptkbp:organism gptkb:Homo_sapiens
gptkbp:orthologInMouse Plcd1
gptkbp:proteinFamily gptkb:phospholipase_C_family
gptkbp:UniProtID Q00973
gptkbp:bfsParent gptkb:phospholipase_C
gptkbp:bfsLayer 6