Statements (30)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
gptkb:enzyme |
| gptkbp:alternativeName |
gptkb:PRKCQ
gptkb:Protein_kinase_C_theta_type |
| gptkbp:associatedWith |
autoimmune diseases
allergic inflammation |
| gptkbp:biologicalProcess |
serine/threonine kinase activity
|
| gptkbp:discoveredIn |
1990s
|
| gptkbp:encodedBy |
gptkb:PRKCQ_gene
|
| gptkbp:expressedIn |
gptkb:skeletal_muscle
T lymphocytes |
| gptkbp:function |
signal transduction
T cell activation regulation of immune response |
| https://www.w3.org/2000/01/rdf-schema#label |
PKC-theta
|
| gptkbp:involvedIn |
NF-κB activation
IL-2 production AP-1 activation |
| gptkbp:locale |
gptkb:immunological_synapse
|
| gptkbp:locatedOnChromosome |
gptkb:chromosome_10q21
|
| gptkbp:memberOf |
gptkb:protein_kinase_C_family
|
| gptkbp:orthologIn |
gptkb:mouse
right |
| gptkbp:phosphorylates |
various substrates
|
| gptkbp:structure |
contains C1, C2, and kinase domains
|
| gptkbp:target |
pharmacological inhibitors
|
| gptkbp:UniProtID |
gptkb:Q04759
|
| gptkbp:bfsParent |
gptkb:PRKCQ
gptkb:HotSpot_Therapeutics |
| gptkbp:bfsLayer |
7
|