Statements (31)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:alias |
H731
MA-3 domain-containing protein Neoplastic transformation inhibitor protein |
| gptkbp:degradedBy |
gptkb:ubiquitin-proteasome_pathway
|
| gptkbp:downregulatedIn |
various cancers
|
| gptkbp:Entrez_Gene_ID |
27250
ENSG00000150593 |
| gptkbp:fullName |
Programmed cell death protein 4
|
| gptkbp:function |
tumor suppressor
translation inhibitor |
| gptkbp:gene |
gptkb:PDCD4
|
| gptkbp:HGNC_ID |
HGNC:8767
|
| https://www.w3.org/2000/01/rdf-schema#label |
PDCD4
|
| gptkbp:inhibitedBy |
gptkb:eIF4A
|
| gptkbp:interactsWith |
gptkb:eIF4A
miR-21 |
| gptkbp:length |
469 amino acids
|
| gptkbp:locatedOnChromosome |
10
|
| gptkbp:location |
10q24
|
| gptkbp:OMIM |
608479
|
| gptkbp:organism |
gptkb:Homo_sapiens
|
| gptkbp:phosphorylates |
gptkb:S6K1
|
| gptkbp:regulates |
apoptosis
cell proliferation metastasis invasion |
| gptkbp:UniProtID |
Q53EL6
|
| gptkbp:bfsParent |
gptkb:Ribosomal_protein_S6_kinase
gptkb:Ribosomal_protein_S6_kinase_beta-1 |
| gptkbp:bfsLayer |
7
|