Statements (32)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:gene
|
| gptkbp:alsoKnownAs |
gptkb:PD-L2
gptkb:CD273 gptkb:B7-DC |
| gptkbp:associatedWith |
cancer immune evasion
|
| gptkbp:discoveredIn |
2001
|
| gptkbp:encodes |
Programmed cell death 1 ligand 2
|
| gptkbp:Entrez_Gene_ID |
80380
ENSG00000197646 |
| gptkbp:expressedIn |
dendritic cells
macrophages some tumor cells |
| gptkbp:function |
immune checkpoint protein
regulation of T cell function |
| gptkbp:geneType |
protein-coding
|
| https://www.w3.org/2000/01/rdf-schema#label |
PDCD1LG2
|
| gptkbp:inhibitedBy |
T cell activation
|
| gptkbp:interactsWith |
gptkb:PD-1
|
| gptkbp:involvedIn |
immune response modulation
|
| gptkbp:locatedOnChromosome |
gptkb:9p24.1
gptkb:chromosome_9 |
| gptkbp:memberOf |
gptkb:B7_family
|
| gptkbp:OMIM |
605762
|
| gptkbp:orthologInMouse |
Pdcd1lg2
|
| gptkbp:regulates |
cytokine production
T cell proliferation |
| gptkbp:species |
gptkb:Homo_sapiens
|
| gptkbp:target |
immunotherapy
|
| gptkbp:transmembraneDomains |
true
|
| gptkbp:UniProtID |
Q9BQ51
|
| gptkbp:bfsParent |
gptkb:9p24.1
|
| gptkbp:bfsLayer |
7
|