gptkbp:instanceOf
|
gptkb:protein
|
gptkbp:alternativeName
|
gptkb:AD3L
gptkb:STM2
PS-2
|
gptkbp:associatedWith
|
gptkb:Alzheimer's_disease
|
gptkbp:biologicalProcess
|
gptkb:Notch_signaling_pathway
protein processing
aspartic-type endopeptidase activity
amyloid-beta metabolic process
|
gptkbp:cellularComponent
|
gptkb:Golgi_apparatus_membrane
endoplasmic reticulum membrane
integral component of membrane
|
gptkbp:discoveredIn
|
1995
|
gptkbp:Entrez_Gene_ID
|
ENSP00000361736
56643
|
gptkbp:enzymeClassification
|
EC 3.4.23.-
|
gptkbp:function
|
Component of the gamma-secretase complex
|
gptkbp:gene
|
gptkb:PSEN2
|
gptkbp:HGNC_ID
|
9509
|
https://www.w3.org/2000/01/rdf-schema#label
|
P49763
|
gptkbp:length
|
448
|
gptkbp:locatedOnChromosome
|
1
|
gptkbp:location
|
1q42.13
|
gptkbp:OMIM
|
gptkb:600759
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
gptkbp:protein_name
|
Presenilin-2
|
gptkbp:RefSeq
|
NP_000435.1
|
gptkbp:sequenceStatus
|
reviewed
|
gptkbp:subunit
|
gptkb:gamma-secretase_complex
|
gptkbp:UniProtID
|
gptkb:P49763
|
gptkbp:bfsParent
|
gptkb:placental_growth_factor_(PlGF)
gptkb:placental_growth_factor
gptkb:PlGF
|
gptkbp:bfsLayer
|
7
|