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gptkbp:instanceOf
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UniProt accession number
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gptkbp:alternativeName
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gptkb:Calgranulin-A
gptkb:Migration_inhibitory_factor-related_protein_8
Cystic fibrosis antigen
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gptkbp:associatedWith
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gptkb:Cystic_fibrosis
Rheumatoid arthritis
Inflammatory bowel disease
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gptkbp:calciumBinding
|
Yes
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gptkbp:database
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gptkb:UniProtKB/Swiss-Prot
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gptkbp:Entrez_Gene_ID
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6279
ENSG00000143546
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gptkbp:expressedIn
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Expressed in monocytes
Highly expressed in neutrophils
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gptkbp:family
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gptkb:S100_protein_family
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gptkbp:function
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Involved in the regulation of inflammatory processes and immune response
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gptkbp:gene
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gptkb:S100A8
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gptkbp:GO
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GO:0005615 (extracellular space)
GO:0006954 (inflammatory response)
GO:0005515 (protein binding)
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gptkbp:HGNC_ID
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10498
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https://www.w3.org/2000/01/rdf-schema#label
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P33681
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gptkbp:InterPro
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gptkb:IPR002048
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gptkbp:length
|
93 amino acids
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gptkbp:locatedOnChromosome
|
1q21
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gptkbp:metalBinding
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gptkb:Calcium
Copper
Zinc
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gptkbp:molecularWeight
|
10,835 Da
|
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gptkbp:OMIM
|
123885
|
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gptkbp:organism
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gptkb:Homo_sapiens
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gptkbp:pathology
|
Associated with inflammatory diseases
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gptkbp:PDB
|
1MR8
1XK4
4GGF
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gptkbp:postTranslationalModification
|
Phosphorylation
Oxidation
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gptkbp:protein_name
|
gptkb:Protein_S100-A8
|
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gptkbp:proteinFamily
|
PF00062
|
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gptkbp:refersTo
|
Human protein S100A8
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gptkbp:RefSeq
|
NP_002953.1
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gptkbp:reviewedBy
|
Yes
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gptkbp:sequenceStatus
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Complete
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gptkbp:structure
|
Forms heterodimer with S100A9
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gptkbp:subcellularLocation
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gptkb:Cytoplasm
Secreted
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gptkbp:tissue_specificity
|
gptkb:Spleen
gptkb:Blood
gptkb:Placenta
Lung
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gptkbp:UniGene
|
Hs.654
|
|
gptkbp:UniProt_entry_name
|
S10A8_HUMAN
|
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gptkbp:bfsParent
|
gptkb:CD80
|
|
gptkbp:bfsLayer
|
7
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