Statements (35)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:alsoKnownAs |
gptkb:B7-1
|
| gptkbp:binds |
gptkb:CD28
gptkb:CTLA-4 |
| gptkbp:biologicalProcess |
immune system process
receptor binding |
| gptkbp:cellularComponent |
gptkb:plasma_membrane
|
| gptkbp:discoveredBy |
gptkb:Lieping_Chen
|
| gptkbp:discoveredIn |
1992
|
| gptkbp:Entrez_Gene_ID |
gptkb:ENSG00000121594
941 |
| gptkbp:expressedIn |
gptkb:B_cells
dendritic cells macrophages antigen-presenting cells |
| gptkbp:foundIn |
humans
mice |
| gptkbp:function |
immune response regulation
costimulatory molecule |
| gptkbp:gene |
gptkb:CD80_gene
|
| gptkbp:GOID |
gptkb:GO:0001772
|
| gptkbp:HGNC_ID |
gptkb:HGNC:1709
|
| https://www.w3.org/2000/01/rdf-schema#label |
CD80
|
| gptkbp:locatedOnChromosome |
gptkb:chromosome_3_(human)
|
| gptkbp:molecularWeight |
60 kDa
|
| gptkbp:OMIM |
112203
|
| gptkbp:PDB |
gptkb:1DR9
|
| gptkbp:role |
immunotherapy
autoimmune diseases T cell activation transplant rejection |
| gptkbp:structure |
type I transmembrane glycoprotein
|
| gptkbp:UniProtID |
gptkb:P33681
|
| gptkbp:bfsParent |
gptkb:CTLA-4
|
| gptkbp:bfsLayer |
6
|