|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:alternativeName
|
Integrin beta-2
Leukocyte adhesion deficiency antigen
|
|
gptkbp:associatedWith
|
Leukocyte adhesion deficiency type 1
|
|
gptkbp:biologicalProcess
|
immune response
cell adhesion
|
|
gptkbp:cellularComponent
|
gptkb:plasma_membrane
|
|
gptkbp:component
|
LFA-1 (lymphocyte function-associated antigen 1)
p150,95
Mac-1 (macrophage-1 antigen)
|
|
gptkbp:disulfideBond
|
present
|
|
gptkbp:EC_number
|
none
|
|
gptkbp:Entrez_Gene_ID
|
3689
ENSG00000160255
|
|
gptkbp:expressedIn
|
gptkb:leukocytes
monocytes
lymphocytes
neutrophils
|
|
gptkbp:function
|
Adhesion molecule involved in leukocyte adhesion and migration
|
|
gptkbp:glycosylation
|
present
|
|
gptkbp:goMolecularFunction
|
integrin binding
|
|
gptkbp:hasGeneName
|
gptkb:ITGB2
|
|
gptkbp:hasIsoform
|
2
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
P05107 (CD18)
|
|
gptkbp:interactsWith
|
gptkb:ICAM1
gptkb:ICAM3
ICAM2
|
|
gptkbp:lastAnnotationUpdate
|
2021-02-10
|
|
gptkbp:latestReleaseVersion
|
2001-11-01
|
|
gptkbp:length
|
769 amino acids
|
|
gptkbp:locatedOnChromosome
|
21q22.3
|
|
gptkbp:location
|
gptkb:cell_membrane
|
|
gptkbp:molecularWeight
|
85 kDa
|
|
gptkbp:mutationAssociation
|
immunodeficiency
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologInMouse
|
Itgb2
|
|
gptkbp:PDB
|
3K6S
5ES4
|
|
gptkbp:postTranslationalModification
|
gptkb:N-glycosylation
Disulfide bond
|
|
gptkbp:proteinFamily
|
integrin beta chain family
|
|
gptkbp:RefSeq
|
NP_000201.2
|
|
gptkbp:reviewedBy
|
gptkb:UniProtKB/Swiss-Prot
|
|
gptkbp:sequenceStatus
|
complete
|
|
gptkbp:sequenceVersion
|
2
|
|
gptkbp:signalPeptide
|
present
|
|
gptkbp:subunit
|
integrin heterodimer
|
|
gptkbp:UniProtID
|
P05107
|
|
gptkbp:bfsParent
|
gptkb:LFA-1
|
|
gptkbp:bfsLayer
|
8
|