|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:alternativeName
|
gptkb:CD3-epsilon
gptkb:IMD18
gptkb:T3E
|
|
gptkbp:antigen
|
gptkb:CD3_epsilon
|
|
gptkbp:associatedWith
|
Immunodeficiency 18 (IMD18)
|
|
gptkbp:biologicalProcess
|
immune response
T cell activation
|
|
gptkbp:cellularComponent
|
gptkb:T-cell_receptor_complex
gptkb:plasma_membrane
integral component of membrane
|
|
gptkbp:disulfideBond
|
Yes
|
|
gptkbp:Entrez_Gene_ID
|
916
ENSG00000198851
|
|
gptkbp:function
|
Part of the T-cell receptor-CD3 complex involved in T-cell activation
|
|
gptkbp:gene
|
gptkb:CD3E
|
|
gptkbp:goMolecularFunction
|
protein binding
|
|
gptkbp:hasIsoform
|
1
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
P04234 (CD3E HUMAN)
|
|
gptkbp:interactsWith
|
gptkb:CD3G
gptkb:CD3D
CD247 (CD3Z)
TCR alpha/beta
TCR gamma/delta
|
|
gptkbp:locatedOnChromosome
|
11q23.3
|
|
gptkbp:molecularWeight
|
23 kDa
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologInMouse
|
gptkb:Cd3e
|
|
gptkbp:pathway
|
gptkb:T_cell_receptor_signaling_pathway
Adaptive immune system
|
|
gptkbp:PDB
|
gptkb:1SY6
1XIW
|
|
gptkbp:postTranslationalModification
|
Phosphorylation
Glycosylation
|
|
gptkbp:protein_name
|
gptkb:T-cell_surface_glycoprotein_CD3_epsilon_chain
|
|
gptkbp:RefSeq
|
NP_000724.1
|
|
gptkbp:reviewedBy
|
Yes
|
|
gptkbp:sequence
|
207
|
|
gptkbp:sequenceStatus
|
Complete
|
|
gptkbp:signalPeptide
|
Yes
|
|
gptkbp:subunit
|
gptkb:T-cell_receptor-CD3_complex
|
|
gptkbp:tissue_specificity
|
gptkb:Thymus
gptkb:Spleen
gptkb:T-lymphocytes
|
|
gptkbp:transmembraneDomains
|
Yes
|
|
gptkbp:UniProt_entry_name
|
CD3E_HUMAN
|
|
gptkbp:UniProtID
|
gptkb:P04234
|
|
gptkbp:bfsParent
|
gptkb:T-cell_receptor-CD3_complex
|
|
gptkbp:bfsLayer
|
8
|