|
gptkbp:instanceOf
|
gptkb:UniProt_accession_number
|
|
gptkbp:alternativeName
|
gptkb:IFNB2
gptkb:HGF
B-cell stimulatory factor 2
BSF-2
Hybridoma growth factor
Interleukin HP-1
|
|
gptkbp:associatedWith
|
gptkb:Castleman_disease
Rheumatoid arthritis
COVID-19 cytokine storm
Systemic juvenile idiopathic arthritis
|
|
gptkbp:chain
|
29-212
|
|
gptkbp:database
|
gptkb:UniProtKB/Swiss-Prot
|
|
gptkbp:disulfideBond
|
45-51
74-84
|
|
gptkbp:Entrez_Gene_ID
|
gptkb:ENSG00000136244
3569
|
|
gptkbp:function
|
Cytokine with a wide variety of biological functions
|
|
gptkbp:gene
|
gptkb:IL6
|
|
gptkbp:glycosylation
|
N-linked (Asn-44)
|
|
gptkbp:GO
|
gptkb:GO:0005125
gptkb:GO:0005126
GO:0006954
GO:0006955
|
|
gptkbp:HGNC_ID
|
6018
|
|
gptkbp:KEGGID
|
hsa:3569
|
|
gptkbp:literatureReference
|
PMID: 2468186
PMID: 3264197
PMID: 6209360
PMID: 6338826
|
|
gptkbp:locatedOnChromosome
|
7p15.3
|
|
gptkbp:mass
|
23,720 Da
|
|
gptkbp:OMIM
|
147620
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:PDB
|
gptkb:1ALU
1IL6
1P9M
2IL6
4NI9
|
|
gptkbp:protein_name
|
gptkb:Interleukin-6
|
|
gptkbp:Reactome
|
R-HSA-449147
|
|
gptkbp:refersTo
|
gptkb:Interleukin-6
|
|
gptkbp:RefSeq
|
NP_000591.1
|
|
gptkbp:sequence
|
212
|
|
gptkbp:signalPeptide
|
1-28
|
|
gptkbp:status
|
Reviewed
|
|
gptkbp:subcellularLocation
|
Secreted
|
|
gptkbp:UniGene
|
gptkb:Hs.654592
|
|
gptkbp:UniProt_entry_name
|
IL6_HUMAN
|
|
gptkbp:bfsParent
|
gptkb:ND5
|
|
gptkbp:bfsLayer
|
7
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
P03915
|