|
gptkbp:instanceOf
|
gptkb:gene
|
|
gptkbp:alsoKnownAs
|
gptkb:interleukin-6
gptkb:IL-6
|
|
gptkbp:associatedWith
|
gptkb:systemic_lupus_erythematosus
autoimmune diseases
immune response
rheumatoid arthritis
COVID-19 severity
|
|
gptkbp:discoveredBy
|
Tada et al.
|
|
gptkbp:encodes
|
interferon beta-2 protein
|
|
gptkbp:Entrez_Gene_ID
|
3569
|
|
gptkbp:expressedIn
|
various tissues
|
|
gptkbp:firstDescribed
|
1986
|
|
gptkbp:function
|
cytokine activity
|
|
gptkbp:HGNC_ID
|
6019
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
IFNB2
|
|
gptkbp:involvedIn
|
inflammatory response
regulation of immune system
|
|
gptkbp:length
|
212 amino acids
|
|
gptkbp:locatedOnChromosome
|
gptkb:chromosome_7
7p15.3
|
|
gptkbp:OMIM
|
147620
|
|
gptkbp:orthologInMouse
|
Il6
|
|
gptkbp:proteinFamily
|
cytokine family
interferon family
|
|
gptkbp:regulates
|
fever
inflammation
B cell differentiation
acute phase response
|
|
gptkbp:target
|
gptkb:tocilizumab
gptkb:sarilumab
gptkb:siltuximab
|
|
gptkbp:UniProtID
|
gptkb:P05231
|
|
gptkbp:bfsParent
|
gptkb:HGNC:5973
gptkb:HGNC:6348
gptkb:IL6_gene
gptkb:P05231
|
|
gptkbp:bfsLayer
|
7
|