Statements (36)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:gene
|
| gptkbp:alsoKnownAs |
gptkb:interleukin-6
gptkb:IL-6 |
| gptkbp:associatedWith |
gptkb:systemic_lupus_erythematosus
gptkb:immune_response autoimmune diseases rheumatoid arthritis COVID-19 severity |
| gptkbp:discoveredBy |
Tada et al.
|
| gptkbp:encodes |
interferon beta-2 protein
|
| gptkbp:Entrez_Gene_ID |
3569
|
| gptkbp:expressedIn |
various tissues
|
| gptkbp:firstDescribed |
1986
|
| gptkbp:function |
cytokine activity
|
| gptkbp:HGNC_ID |
6019
|
| gptkbp:involvedIn |
inflammatory response
regulation of immune system |
| gptkbp:length |
212 amino acids
|
| gptkbp:locatedOnChromosome |
gptkb:chromosome_7
7p15.3 |
| gptkbp:OMIM |
147620
|
| gptkbp:orthologInMouse |
Il6
|
| gptkbp:proteinFamily |
gptkb:cytokine_family
interferon family |
| gptkbp:regulates |
fever
inflammation B cell differentiation acute phase response |
| gptkbp:target |
gptkb:tocilizumab
gptkb:sarilumab gptkb:siltuximab |
| gptkbp:UniProtID |
gptkb:P05231
|
| gptkbp:bfsParent |
gptkb:HGNC:5973
gptkb:HGNC:6348 |
| gptkbp:bfsLayer |
7
|
| https://www.w3.org/2000/01/rdf-schema#label |
IFNB2
|